Fructokinase

spinqualitylabelsall models Se-Met fructokinase dimer complex with ATP, phosphate and K+ ion (purple), 3lki Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Function Fructokinase (FRK) catalyzes the phosphorylation of fructose to fructose-1-phosphate using ATP as phosphate source in plants, bacteria and animals. In plants and bacteria FRK regulates starch synthesis. In animals it produces oxalate and its precursors. Relevance Inhibitors of FRK C may block sugar-associated metabolic syndromes. Disease FRK deficiency in the liver causes the inherited metabolic disorder Fructosuria.

3D structures of fructokinase

Updated on 08-June-2016

2qhp – FRK – Bacterioides thetaiotamicron
3ljs – XfFRK – Xylella fastidiosa
3hj6 – FRK – Halothermothrix orenii
3lki – XfFRK + ATP
3lm9 - BsFRK + ATP + fructose – Bacillus subtilis
3ohr - BsFRK + ADP
2v78, 2var – FRK – Sulfolobus solfataricus
3c8u – FRK – Silicibacter

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