4f46 | pdb_00004f46

Crystal structure of wild type human CD38 in complex with NAADP and ADPRP

spinqualitylabelsall models 4f46, resolution 1.69Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 4f46 is a 2 chain structure with sequence from Human. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: DN4, DVN Related: 4f45 Gene: CD38 (HUMAN) Activity: NAD(+) nucleosidase, with EC number 3.2.2.5 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [CD38_HUMAN] Synthesizes cyclic ADP-ribose, a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system. See Also Cluster of Differentiation CD38

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