4ez8 | pdb_00004ez8

Crystal structure of mouse thymidylate sythase in ternary complex with N(4)-hydroxy-2'-deoxycytidine-5'-monophosphate and the cofactor product, dihydrofolate

spinqualitylabelsall models 4ez8, resolution 1.17Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 4ez8 is a 1 chain structure with sequence from Lk3 transgenic mice. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: DHF, GOL, NOH Related: 4ein Gene: Tyms (LK3 transgenic mice) Activity: Thymidylate synthase, with EC number 2.1.1.45 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [TYSY_MOUSE] Contributes to the de novo mitochondrial thymidylate biosynthesis pathway (By similarity). See Also Thymidylate synthase

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