Structural highlights
4eeq is a 1 chain structure with sequence from "enterococcus_proteiformis"_thiercelin_and_jouhaud_1903 "enterococcus proteiformis" thiercelin and jouhaud 1903. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
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| Ligands: | 0OX, NMN, SO4 |
| Related: | 4efb, 4efe |
| Gene: | ligA, EF_0722 ("Enterococcus proteiformis" Thiercelin and Jouhaud 1903) |
| Activity: | DNA ligase (NAD(+)), with EC number 6.5.1.2 |
| Resources: | FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT |
Function
[DNLJ_ENTFA] DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity).
See Also
