4nmh | pdb_00004nmh

11-beta-HSD1 in complex with a 3,3-Di-methyl-azetidin-2-one

spinqualitylabelsall models 4nmh, resolution 2.90Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 4nmh is a 4 chain structure with sequence from Lk3 transgenic mice. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: 2KG, NDP, SO4 Gene: Hsd11b1, Hsd11 (LK3 transgenic mice) Activity: 11-beta-hydroxysteroid dehydrogenase, with EC number 1.1.1.146 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [DHI1_MOUSE] Catalyzes reversibly the conversion of cortisol to the inactive metabolite cortisone. See Also Hydroxysteroid dehydrogenase

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