Structural highlights
2x5k is a 4 chain structure with sequence from Ecoli. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
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| Ligands: | CL, EDO, GOL, PEG, PG4, PGE |
| Related: | 2x5j, 2x5m |
| Activity: | Erythrose-4-phosphate dehydrogenase, with EC number 1.2.1.72 |
| Resources: | FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT |
Function
[E4PD_ECOLI] Catalyzes the NAD-dependent conversion of D-erythrose 4-phosphate to 4-phosphoerythronate.[1] [2]
References
- ↑ Boschi-Muller S, Azza S, Pollastro D, Corbier C, Branlant G. Comparative enzymatic properties of GapB-encoded erythrose-4-phosphate dehydrogenase of Escherichia coli and phosphorylating glyceraldehyde-3-phosphate dehydrogenase. J Biol Chem. 1997 Jun 13;272(24):15106-12. PMID:9182530
- ↑ Yang Y, Zhao G, Man TK, Winkler ME. Involvement of the gapA- and epd (gapB)-encoded dehydrogenases in pyridoxal 5'-phosphate coenzyme biosynthesis in Escherichia coli K-12. J Bacteriol. 1998 Aug;180(16):4294-9. PMID:9696782
