4h80 | pdb_00004h80

Crystal structure of human ALDH3A1 with its isozyme selective inhibitor - N-[4-(4-methylsulfonyl-2-nitroanilino)phenyl]acetamide

spinqualitylabelsall models 4h80, resolution 2.50Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 4h80 is a 8 chain structure with sequence from Human. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: 04T Related: 3sza, 3szb Gene: ALDH3, ALDH3A1 (HUMAN) Activity: Aldehyde dehydrogenase (NAD(P)(+)), with EC number 1.2.1.5 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [AL3A1_HUMAN] ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. This protein preferentially oxidizes aromatic aldehyde substrates. It may play a role in the oxidation of toxic aldehydes. See Also Aldehyde dehydrogenase

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