Structural highlights
3tz5 is a 1 chain structure with sequence from Buffalo rat. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
|
| Ligands: | ADP, CLT, K, MG |
| Related: | 3tz0, 3tz2, 3tz4, 4dzy, 4h7q, 4h81, 4h85 |
| Gene: | Bckdk (Buffalo rat) |
| Activity: | [3-methyl-2-oxobutanoate_dehydrogenase_(acetyl-transferring)_kinase [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase], with EC number 2.7.11.4 |
| Resources: | FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT |
Function
[BCKD_RAT] Catalyzes the phosphorylation and inactivation of the branched-chain alpha-ketoacid dehydrogenase complex, the key regulatory enzyme of the valine, leucine and isoleucine catabolic pathways. Key enzyme that regulate the activity state of the BCKD complex.
