5d1x | pdb_00005d1x

IsdB NEAT2 bound by D4-30

spinqualitylabelsall models 5d1x, resolution 3.21Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 5d1x is a 5 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Related: 5d1q, 5d1z Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [ISDB_STAA3] Seems to function as the primary receptor for hemoglobin since its inactivation inhibits the ability of S.aureus to bind hemoglobin. Binds hemoglobin in a dose-dependent way. Required for S.aureus growth using hemoglobin as the sole iron source. Also required for virulence. IsdA and/or IsdB promote resistance to hydrogen peroxide and killing by neutrophils (By similarity).

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