5fjv | pdb_00005fjv

Crystal structure of the extracellular domain of alpha2 nicotinic acetylcholine receptor in pentameric assembly

spinqualitylabelsall models 5fjv, resolution 3.20Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 5fjv is a 5 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: EPJ Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease [ACHA2_HUMAN] Autosomal dominant nocturnal frontal lobe epilepsy. The disease is caused by mutations affecting the gene represented in this entry. Function [ACHA2_HUMAN] After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.

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