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TATA-Binding Protein (TBP) binds to TATA box in DNA and is part of the RNA polymerase II transcription complex. The transcription factor proteins are named TFIIA to TFIIH. TBP is part of TFIID. Its interaction with DNA initiates the DNA strands separation[1]. See also
Additional information
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Called the TATA box to represent its thymine-adenine-thymine-adenine-adenine (TATAA) nucleotide motif
interact with the phosphate groups
phenylalanine amino acids
asparagine amino acids
two symmetrical halves.
- ↑ Caporaso N. Genetic susceptibility in the occupational setting: introduction to the workshop. Med Lav. 1995 May-Jun;86(3):199-206. PMID:7565278
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3D Structures of TATA-binding protein
Updated on 07-September-2016
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- TBP
- TBP+DNA TATA box
- 1ytb - yTBP + DNA TATA
- 1cdw - hTBP core domain+ DNA TATA - human
- 1tgh - hTBP + DNA TATA
- 1qn5, 1qn6, 1qn7, 1qn8, 1qn9, 1qna, 1qnb, 1qnc, 1qne, 1qn3, 1qn4, 1vto - AtTBP + DNA TATA
- TBP+DNA TATA box +TFIIA
- 1rm1 – yTBP+TFIIA α, β, γ chains+ DNA TATA
- 1ytf - yTBP+TFIIA + DNA TATA
- 1nh2 – yTBP C-terminal+TFIIA α, β, γ chains+ DNA TATA
- 1nvp - hTBP C-terminal+ TFIIA α, β, γ chains+ DNA TATA
- 1jfi - hTBP C-terminal+ TFIIA NC2+ DNA TATA
- TBP+DNA TATA box +TFIIB
- 1ngm - yTBP C-terminal+TFIIIB BRF1 subunit + DNA TATA
- 1tba – yTBP core domain+TAFII230 fragment - NMR
- 1c9b - hTBP C-terminal+TFIIBC+adenovirus major late promoter
- 1vol – AtTBP+hTFIIB+DNA TATA
- 1ais, 1d3u - PwTBP N-terminal+ TFIIB C-terminal + DNA TATA
- 1tba – yTBP core domain+TAFII230 fragment - NMR
References
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