2j9a | pdb_00002j9a
BLLAP IN COMPLEX WITH MICROGININ FR1
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Overview
Natural bioactive compounds are of general interest for pharmaceutical, research because they may serve as leads in drug development campaigns., Among them, microginins are linear peptides known to inhibit various, exopeptidases. The crystal structure of microginin FR1 from Microcystis, sp. bound to bovine lens leucine aminopeptidase was established at 1.73, Angstrom resolution. The observed binding structure could be beneficial, for the design of potent aminopeptidase inhibitors.
About this Structure
2J9A is a [Single protein] structure of sequence from [Bos taurus] with CL, ZN, DMS, AHY and MPD as [ligands]. Full crystallographic information is available from [OCA].
Reference
Binding structure of the leucine aminopeptidase inhibitor microginin FR1., Kraft M, Schleberger C, Weckesser J, Schulz GE, FEBS Lett. 2006 Dec 22;580(30):6943-7. Epub 2006 Dec 4. PMID:17157838
Page seeded by OCA on Mon Oct 29 17:19:47 2007
