5t1i | pdb_00005t1i

CBX3 chromo shadow domain in complex with histone H3 peptide

spinqualitylabelsall models 5t1i, resolution 1.60Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 5t1i is a 3 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: UNX NonStd Res: AAR, N7P Related: 5t1g Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [CBX3_HUMAN] Seems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.

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