5fcr | pdb_00005fcr

MOUSE COMPLEMENT FACTOR D

spinqualitylabelsall models 5fcr, resolution 1.25Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 5fcr is a 4 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: DMS, EPE, GOL, SO4 Activity: Complement factor D, with EC number 3.4.21.46 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [CFAD_MOUSE] Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway.

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