UvrABC

spinqualitylabelsall models UvrA complex with DNA, pyrophosphate and Zn+2 ion (grey) 3pih Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Function UvrABC endonuclease is an E. coli enzyme complex involved in DNA repair. UvrABC removes 12 nucleotides around a DNA mutation replacing them with the correct one. For details on the UvrA-UvrB complex see UvrA-UvrB interaction domains. Structural highlights UvrA contains several domains: UvrB-binding, DNA-binding and two ATP-binding domains.

3D structures of UvrABC

Updated on 12-December-2016

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• UvrA
  • UvrA-UvrB interaction domains – TmUvrA + DNA – Thermotoga maritima
    
  • 3zqj – UvrA – Mycobacterium tuberculosis
    
  • 4dfc – EcUvrA + Transcription-repair-coupling factor – Escherichia coli
    
  • 2r6f – BstUvrA – Bacillus stearothermophilus
    
  • 3ux8 – GeUvrA - Geobacillus
    
• UvrB
  • 1d2m, 1c4o – UvrB – Thermus thermophilus
    
  • 1d9x – BcUvrB – Bacillus caldotenax
    
  • 1t5l – BcUvrB (mutant)
    
  • 1qoj – EcUvrB C terminal
    
  • 1e52 – EcUvrB C terminal - NMR
    
  • 1d9z – BcUvrB + ATP
    
  • 2fdc – BcUvrB + DNA
    
  • 2d7d, 2nmv, 3v4r – BsUvrB + DNA – Bacillus subtilis
    
• UvrC
  • 1kft – EcUvrC C terminal
    
  • 2nrr, 2nrt, 2nrv, 2nrw, 2nrx, 2nrz – TmUvrC C terminal
    
  • 1ycz, 1yd0, 1yd1 – TmUvrC N terminal
    
  • 1yd2, 1yd3, 1yd4, 1yd5 – TmUvrC N terminal (mutant)
    
  • 1yd6 – BcUvrC N terminal
    
  • 3c65 – BstUvrC
    
• UvrA-UvrB
  • 3fpn – BstUvrA + UvrB
    
  • 3uwx – GeUvrA + UvrB
    

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