ERGIC-53

spinqualitylabelsall models Caption for this structure Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Function ER-Golgi Intermediate Compartment-53 (ERGIC-53) is a transmembrane protein which acts as a receptor of glycoproteins and transports them from the ER to ER-Golgi Intermediate Compartment and Golgi. Relevance Some ER storage diseases have relationship with EGRIC-53. Structural highlights ERGIC-53 contains an N-terminal signal sequence, a calcium-dependent and pH-sensitive carbohydrate recognition domain (CRD), a stalk region, a transmembrane domain and a short cytoplasmic domain.

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman