5fql | pdb_00005fql

Insights into Hunter syndrome from the structure of iduronate-2- sulfatase

spinqualitylabelsall models 5fql, resolution 2.30Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 5fql is a 1 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: CA, CL, NAG, FUC NonStd Res: ALS Activity: Iduronate-2-sulfatase, with EC number 3.1.6.13 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease [IDS_HUMAN] Mucopolysaccharidosis type 2, attenuated form;Mucopolysaccharidosis type 2, severe form. The disease is caused by mutations affecting the gene represented in this entry. Function [IDS_HUMAN] Required for the lysosomal degradation of heparan sulfate and dermatan sulfate.

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