5m0j | pdb_00005m0j

Crystal structure of the cytoplasmic complex with She2p, She3p, and the ASH1 mRNA E3-localization element

spinqualitylabelsall models 5m0j, resolution 2.80Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 5m0j is a 10 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: MG Related: 5m0h, 5m0i Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [SHE2_YEAS1] RNA-binding protein that binds specific mRNAs including the ASH1 mRNA, coding for a repressor of the HO endonuclease. Part of the mRNA localization machinery that restricts accumulation of certain proteins to the bud and in the daughter cell. Recruits the MYO4-SHE3 complex to the ASH1 mRNA. Recruits also LOC1 and PUF6 to ASH1 mRNA, which are required for translational repression of this mRNA (By similarity).

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