1dc0 | pdb_00001dc0

CRYSTAL STRUCTURE OF AN A/B-DNA INTERMEDIATE CATGGGCCCATG

spinqualitylabelsall models 1dc0, resolution 1.30Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 1dc0 is a 2 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Publication Abstract from PubMed The DNA dodecamer CATGGGCCCATG in a crystal structure of resolution 1.3 A has a conformation intermediate between A and B DNA. This trapping of a stable intermediate suggests that the A and B DNA families are not discrete, as previously believed. The structure supports a base-centered rather than a backbone-centered mechanism for the A <--> B transition mediated by guanine tracts. Interconversion between A and B DNA provides another means for regulating protein-DNA recognition. The structure of a stable intermediate in the A <--> B DNA helix transition.,Ng HL, Kopka ML, Dickerson RE Proc Natl Acad Sci U S A. 2000 Feb 29;97(5):2035-9. PMID:10688897 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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