1srs | pdb_00001srs
SERUM RESPONSE FACTOR (SRF) CORE COMPLEXED WITH SPECIFIC SRE DNA
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| 1srs, resolution 3.200Å | |||||||||||||
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| Ligands: | 5IU, DA, DC, DG, DT | ||||||||||||
| Gene: | SRF CORE (RESIDUES 132-223) (Homo sapiens) | ||||||||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||||||
Overview
The human serum response factor is a transcription factor belonging to the MADS domain protein family with members characterized from the plant and animal kingdoms. The X-ray crystal structure of the serum response factor core in a specific-recognition DNA complex shows that the functions of DNA binding, dimerization and accessory-factor interaction are compactly integrated into a novel protein unit. The intrinsic and induced conformation of the serum response element DNA is the principal DNA feature recognized in the specific complex.
About this Structure
1SRS is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
Structure of serum response factor core bound to DNA., Pellegrini L, Tan S, Richmond TJ, Nature. 1995 Aug 10;376(6540):490-8. PMID:7637780
Page seeded by OCA on Sun Mar 30 23:46:09 2008
