5ily | pdb_00005ily

Tobacco 5-epi-aristolochene synthase with BIS-TRIS buffer molecule and diphosphate (PPi)

spinqualitylabelsall models 5ily, resolution 2.45Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 5ily is a 1 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: BTB, DPO, MG Related: 5ik0, 5ik6, 5ik9, 5ika, 5ikh, 5il3, 5il8, 5ild, 5ilh, 5ili, 5ilj, 5ilk, 5ilz, 5im1 Activity: 5-epiaristolochene synthase, with EC number 4.2.3.61 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [5EAS_TOBAC] Catalyzes the cyclization of trans,trans-farnesyl diphosphate (FPP) to the bicyclic intermediate 5-epi-aristolochene, initial step in the conversion of FPP to the sesquiterpenoid antifungal phytoalexin capsidiol. Produces germacrene A as an enzyme-bound intermediate that is not released by the enzyme, but is further cyclized to produce the bicyclic 5-epi-aristolochene.

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