Structural highlights
5kgl is a 2 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
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| Ligands: | CL, MN, SO4, ZN |
| Related: | 5kgn, 5kgm |
| Activity: | Phosphoglycerate mutase (2,3-diphosphoglycerate-independent), with EC number 5.4.2.12 |
| Resources: | FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT |
Function
[GPMI_CAEEL] Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.[1] [2]
References
- ↑ Zhang Y, Foster JM, Kumar S, Fougere M, Carlow CK. Cofactor-independent phosphoglycerate mutase has an essential role in Caenorhabditis elegans and is conserved in parasitic nematodes. J Biol Chem. 2004 Aug 27;279(35):37185-90. Epub 2004 Jul 2. PMID:15234973 doi:https://dx.doi.org/10.1074/jbc.M405877200
- ↑ Raverdy S, Zhang Y, Foster J, Carlow CK. Molecular and biochemical characterization of nematode cofactor independent phosphoglycerate mutases. Mol Biochem Parasitol. 2007 Dec;156(2):210-6. Epub 2007 Aug 19. PMID:17897734 doi:https://dx.doi.org/10.1016/j.molbiopara.2007.08.002
