Polygalacturonase

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Polygalacturonases (PGs) catalyze the enzymatic depolymerization of pectins – polysaccharides that comprise the plant cell wall. Polymer disassembly of substrates by exo- and endo- PGs is carried out via a hydrolytic mechanism. Degradation of pectins in plant cell walls contributes to ripening of fruits, such as tomatoes and melons (Polygalacturonases: many genes in search of a function).

Function

PGs cleave α-(1-4) – glycosidic bonds between consecutive galacturonic acid residues.

Structural highlights

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Proteopedia Page Contributors and Editors (what is this?)

Marilyn Yoder, Krishna Amin, OCA, Michal Harel, Jaime Prilusky, Joel L. Sussman