Virus protease

Virus proteases include HIV protease, XMRV protease, retropepsin. HIV Protease (HIV-PR) and xenotropic murine leukemia virus protease (XMRV-PR) cleave polyproteins to produce the mature proteins of the virus. Both are aspartyl proteases. The inhibition of HIV-PR results in an uninfectious HIV virion. HIV-1 is found globally while HIV-2, which has lower virulence, is found in West Africa. See also

• Immunodeficiency virus protease
  
• Human Immunodeficiency Virus
  
• HIV-1 protease
  
• HIV Protease Inhibitor Pharmacokinetics
  
• HIV Protease Inhibitor Resistance Profile
  
• HIV Protease Resistance
  
• Molecular Playground/Dengue Virus Protease
  
• Viability of a drug-resistant HIV-1 protease mutant
  
• Molecular Playground/Dengue Virus Protease

3D Structures of Virus proteases

Updated on 18-July-2017

{"openlevels":0}

• HIV-1 protease . See Immunodeficiency virus protease
• HIV-2 protease See Immunodeficiency virus protease
• Feline Immunodeficiency virus protease See Immunodeficiency virus protease

• Simian Immunodeficiency virus protease See Immunodeficiency virus protease
• Xenotropic murine leukemia virus protease
  • 3nr6 – XMRV-PR P14
    
  • 3p1g – XMRV-PR RNase H domain (mutant)
• Rous sarcoma virus protease
  • 1bai – RSVP + polypeptide inhibitor _ Rous sarcoma virus
• Human Cytomegalovirus protease
  • 1cmv, 1lay – CMVP (mutant) – human herpes virus 5
    
  • 1wpo – CMVP
    
  • 2wpo - CMVP (mutant) + inhibitor
• Varicella-Zoster virus protease
  • 1vzv - VZVP (mutant) – human herpes virus
• Equine infectious anemia virus protease
  • 2fmb – EIAVP (mutant) + inhibitor
• Hepatitis A virus protease
  • 2h9h – HAVP residues 1520-1731 (mutant) + polypeptide inhibitor
• Hepatitis C virus protease
  • 2o8m – HCVP (mutant)
    
• Orf 17
  • 3njq – hOrf 17 - human herpes virus 8
• Dengue virus protease
  • 3u1i – DvNs2b + peptide – Dengue virus
    
  • 3u1j – DvNs2b + BPTI
    
  • 2fom - DvNs2b + DvNs3
    
  • 2whx – DvNs3 residues 1475-2092
• Herpes simplex virus protease
  • 1at3 – HSV II – human herpesvirus 2
• Foot-and-Mouth Disease virus protease
  • 2bhg – FMDV – Foot-and-mouth disease virus
• Infectious Bronchitis virus protease
  • 2q6d – IBV – infectious bronchitis virus
    
  • 2q6f – IBV + inhibitor
• Yellowtail ascites virus protease
  • 4izj, 4izk – YAV Vp4 (mutant) – yellowtail ascites virus
• Pseudorabies virus protease
  • 4cx8 – YAV – pseudorabies virus
    

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Jaime Prilusky, Joel L. Sussman