Bacteriorhodopsin

spinqualitylabelsall models Bacteriorhodopsin complex with retinal, 3han Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Function Bacteriorhodopsin (Br) is a membrane protein in Archaea which moves protons across the cell membrane. See also Bacteriorhodopsin (Hebrew). Structural highlights Br is composed of 6 α-helical elements each containing a retinal molecule. The retinal changes its ground state conformation upon binding of a proton, causing the Br to change conformation to the activated state and pump the proton. The retinal interacts predominantly with hydrophobic and aromatic residues (Hydrophobic, Polar).

3D Structures of bacteriorhodopsin

Updated on 27-September-2017

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• Bacteriorhodopsin
  • Bacteriorhodopsin (Hebrew), 3nsb, 3mbv, 1x0s, 1x0i, 1x0k, 1xji, 1iw6, 4fpd, 2i1x, 1kme, 1qm8, 1bm1, 1brr, 2brd, 4hyx, 4xxj, 4y9h, 5a44, 5a45, 5b34, 5b35, 5b6v, 5b6w, 5b6x, 5b6y, 5b6z, 5h2h, 5h2i, 5h2j, 5h2k, 5h2l, 5h2m– HsBr residues 14-261 + lipid + retinal – Halobacterium salinarum
    
  • 3vhz - HsBr (mutant) + lipid + retinal
    
  • 2wjk, 2wjl - HsBr residues 14-261 (mutant) + lipid + retinal
    
  • 3han, 2hao, 3hap, 3haq, 3har, 3has, 3coc, 3cod, 1tn5, 1tn0, 1s51, 1s52, 1s53, 1s54, 1q5i, 1q5j, 1pxr, 1pxs, 3hao, 3utv, 3utw, 3utx, 3uty - HsBr residues 14-261 (mutant) + retinal
    
  • 2ntu, 1py6, 1fbb, 1fbk, 1brx, 1ap9, 1at9, 5br2, 5br5 - HsBr residues 14-261 + retinal
    
  • 4x31, 4x32 - HsBr residues 14-261 + lipid + retinal
    
  • 2at9 - HsBr residues 14-261 + lipid + retinal – Cryo EM
    
  • 1brd - HsBr residues 14-261 + retinal – Cryo EM
    
  • 1s8j, 3t45 - HsBr residues 14-261 (mutant) + lipid + NO3 + retinal
    
  • 1mgy - HsBr residues 14-261 (mutant) + lipid + Br + retinal
    
  • 1s8l - HsBr residues 14-261 (mutant) + lipid + retinal
    
  • 4md1, 4md2, 4ov0 - HsBr residues 14-261 + lipid
    
  • 1qhj - HsBr residues 14-261 + phytanyl derivavative + retinal
    
  • 4hwl – HsBr + heptane + hexane + retinal
    
  • 1r84, 1r2n - HsBr residues 1-232 + retinal – NMR
    
  • 1bct - HsBr residues 163-231 – NMR
    
  • 1bha, 1bhb - HsBr residues 1-71 - NMR
    
  • 1l0m – Br (mutant) – Halobacterium halobium - NMR
    
  • 4pxk - Br (mutant) – Haloarcula marismortuim
    
  • 4qi1, 4qid – HwBr-I – Haloquadratum walsbyi
    
  • 4wav – HwBr-I (mutant)
    
  • 5azd – Br – Thermus thermophilus
    
• Bacteriorhodopsin intermediates
  • 1f50, 1c8r - HsBr-BR residues 18-244 (mutant) + lipid + retinal
    
  • 1c3w - HsBr-BR residues 5-231 + lipid + retinal
    
  • 2zfe – HsBr-K residues 14-261 + lipid + retinal
    
  • 1m0k, 1m0l, 1ixf - HsBr-K residues 1-261 + lipid + retinal
    
  • 1m0m - HsBr-M1 residues 1-261 + lipid + retinal
    
  • 1e0p, 2ntw, 1vjm - HsBr-L residues 18-245 + retinal
    
  • 1ucq, 1iw9, 1o0a – HsBr-L residues 14-261 + lipid + retinal
    
  • 1kg8, 1kg9, 1kgb, 1dze, 1cwq, 2zzl, 2i20, 2i21, 1p8h - HsBr-M residues 13-243 + lipid + retinal
    
  • 1f4z, 1c8s, 1p8i - HsBr-M residues 18-244 (mutant) + lipid + retinal
    
  • 1p8u – HsBr-N residues 14-261 (mutant) + lipid + retinal
    
  • 1jv6, 1jv7, 3vi0 - HsBr-O residues 1-261 (mutant) + lipid + retinal
    
  • 1qko, 1qkp - HsBr residues 14-261 + retinal
    
• Halorhodopsin
  • 3abw, 3a7k, 3vvk – NpBr+ N3 + bacterioruberin + detergent + retinal – Natronomonas pharaonis
    
  • 3qbg, 3qbi, 3qbk, 3qbl - NpBr + bacterioruberin + detergent + retinal
    
  • 2jaf, 2jag, 1e12 - HsBr (mutant) + lipid+ retinal
    
• Sensory rhodopsin II
  • 2ksy – NpBr – NMR
    
  • 2f93, 2f95, 1h2s - BpBr + Br transducer + detergent + retinal
    
  • 3qap, 3qdc - NpBr + eicosane + lipid + retinal
    
  • 4gyc - NpBr + retinal + eicosane + lipid + Br transducer
    
  • 1gu8, 1gue, 1h68, 1jgj - NpBr + retinal
    
  • 1xio - AnBr + detergent + retinal - Anabaena
    
  • 4tl3 - AnBr (mutant) + detergent + retinal
    
  • 2m3g - AnBr + detergent - NMR
    
• Xanthorhodopsin
  • 3ddl – Br + detergent + salinixanthin + retinal – Salinibacter ruber
• Archaerhodopsin
  • 2ei4, 2z55 – HaBr + bacterioruberin + detergent + retinal – Halobacterium
    
  • 1vgo - HaBr + detergent + retinal
    
  • 1uaz - HaBr + retinal
    
• Proteorhodopsin
  • 2l6x - GpPRn + detergents + retinal – Gamma proteobacterium
    
  • 4kly, 4knf - GpPRn + retinal
    
  • 4jq6 – PRn + retinal + lipid
    
• Deltarhodopsin
  • 4fbz - Rn + bacterioruberin + retinal – Haloterrigena thermotolerans
    

See Also

• Rhodopsin
• G protein-coupled receptor

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Wayne Decatur, Jaime Prilusky, Joel L. Sussman