Structural highlights
5nn3 is a 1 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
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| Ligands: | BMA, CL, EDO, FUC, MAN, NAG, PEG, PGE, SO4 |
| NonStd Res: | CSO |
| Activity: | Alpha-glucosidase, with EC number 3.2.1.20 |
| Resources: | FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT |
Disease
[LYAG_HUMAN] Glycogen storage disease due to acid maltase deficiency, infantile onset;Glycogen storage disease due to acid maltase deficiency, juvenile onset;Glycogen storage disease due to acid maltase deficiency, adult onset. The disease is caused by mutations affecting the gene represented in this entry.
Function
[LYAG_HUMAN] Essential for the degradation of glygogen to glucose in lysosomes.
