Structural highlights
3lcf is a 4 chain structure with sequence from Ecoli. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
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| Ligands: | SO4 |
| Related: | 1nal, 3lbc, 3lbm, 3lcg, 3lch, 3lci, 3lcl, 3lcw, 3lcx |
| Gene: | b3225, JW3194, nanA, npl (ECOLI) |
| Activity: | N-acetylneuraminate lyase, with EC number 4.1.3.3 |
| Resources: | FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT |
Function
[NANA_ECOLI] Catalyzes the cleavage of N-acetylneuraminic acid (sialic acid) to form pyruvate and N-acetylmannosamine via a Schiff base intermediate.[HAMAP-Rule:MF_01237]
