5bnd | pdb_00005bnd

Crystal structure of the C-terminal domain of TagH

spinqualitylabelsall models 5bnd, resolution 2.68Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 5bnd is a 3 chain structure with sequence from Staeq. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Gene: SERP1409 (STAEQ) Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Publication Abstract from PubMed The negatively charged bacterial polysaccharides - wall teichoic acids (WTAs) are synthesized intracellularly and exported by a two-component transporter, TagGH, comprising a transmembrane subunit TagG and an ATPase subunit TagH. We determined the crystal structure of the C-terminal domain of TagH (TagH-C) to investigate its function. The structure shows an N-terminal SH3-like subdomain wrapped by a C-terminal subdomain with an anti-parallel beta-sheet and an outer shell of alpha-helices. A stretch of positively charged surface across the subdomain interface is flanked by two negatively charged regions, suggesting a potential binding site for negatively charged polymers, such as WTAs or acidic peptide chains. This article is protected by copyright. All rights reserved. SH3-Like Motif-Containing C-terminal Domain of Staphylococcal Teichoic Acid Transporter Suggests Possible Function.,Ko TP, Tseng ST, Lai SJ, Chen SC, Guan HH, Yang CS, Chen CJ, Chen Y Proteins. 2016 May 23. doi: 10.1002/prot.25074. PMID:27213893 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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