2qux | pdb_00002qux

PP7 coat protein dimer in complex with RNA hairpin

spinqualitylabelsall models 2qux, resolution 2.44Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 2qux is a 18 chain structure with sequence from Bppp7. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: GOL Related: 1dwn, 2qud Gene: PP7 coat protein (BPPP7) Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Publication Abstract from PubMed The cocrystal structure of the PP7 bacteriophage coat protein in complex with its translational operator identifies a distinct mode of sequence-specific RNA recognition when compared to the well-characterized MS2 coat protein-RNA complex. The structure reveals the molecular basis of the PP7 coat protein's ability to selectively bind its cognate RNA, and it demonstrates that the conserved beta-sheet surface is a flexible architecture that can evolve to recognize diverse RNA hairpins. Structural basis for the coevolution of a viral RNA-protein complex.,Chao JA, Patskovsky Y, Almo SC, Singer RH Nat Struct Mol Biol. 2008 Jan;15(1):103-5. Epub 2007 Dec 9. PMID:18066080 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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