Structural highlights
3wic is a 4 chain structure with sequence from Thevo. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
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| Ligands: | 1PE, PGO, ZN |
| Related: | 3wid, 3wie |
| Gene: | gdh, TV1048, TVG1073292 (THEVO) |
| Activity: | Glucose 1-dehydrogenase, with EC number 1.1.1.47 |
| Resources: | FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT |
Function
[Q979W2_THEVO] Catalyzes the NAD(P)(+)-dependent oxidation of D-glucose to D-gluconate via gluconolactone. Can utilize both NAD(+) and NADP(+) as electron acceptor. Is involved in the degradation of glucose through a non-phosphorylative variant of the Entner-Doudoroff pathway (By similarity).[HAMAP-Rule:MF_02127]
