5lbw | pdb_00005lbw

Structure of the human quinone reductase 2 (NQO2) in complex with volitinib

spinqualitylabelsall models 5lbw, resolution 1.90Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 5lbw is a 2 chain structure with sequence from Human. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: FAD, V0L, ZN Gene: NQO2, NMOR2 (HUMAN) Activity: Ribosyldihydronicotinamide dehydrogenase (quinone), with EC number 1.10.5.1 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [NQO2_HUMAN] The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.

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