5vyk | pdb_00005vyk
From Proteopedia
Crystal structure of the BRS domain of BRAF in complex with the CC-SAM domain of KSR1
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Structural highlights
Function[KSR1_HUMAN] Scaffolding protein that is part of a multiprotein signaling complex. Promotes phosphorylation of Raf family members and activation of downstream MAP kinases. Promotes activation of MAPK1 and/or MAPK3, both in response to EGF and to cAMP. Does not have kinase activity by itself.[UniProtKB:Q61097] Contents | ||||||||||||||||||||
This page was last modified 06:28, 15 February 2018.