6bw6 | pdb_00006bw6

Human GPT (DPAGT1) H129 variant in complex with tunicamycin

spinqualitylabelsall models 6bw6, resolution 2.95Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 6bw6 is a 4 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: PGW, TUM Activity: UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase, with EC number 2.7.8.15 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease [GPT_HUMAN] DPAGT1-CDG;Congenital myasthenic syndromes with glycosylation defect. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. Function [GPT_HUMAN] Catalyzes the initial step in the synthesis of dolichol-P-P-oligosaccharides.

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