2fk6 | pdb_00002fk6
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| 2fk6, resolution 2.90Å | |||||||||||||
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| Ligands: | A, C, G, GOL, MES, U, ZN | ||||||||||||
| Gene: | RNZ (Bacillus subtilis) | ||||||||||||
| Activity: | Ribonuclease Z, with EC number 3.1.26.11 | ||||||||||||
| Related: | 1Y44, 1WW1
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| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||||||
Crystal Structure of RNAse Z/tRNA(Thr) complex
Overview
The highly conserved ribonuclease RNase Z catalyzes the endonucleolytic removal of the 3' extension of the majority of tRNA precursors. Here we present the structure of the complex between Bacillus subtilis RNase Z and tRNA(Thr), the first structure of a ribonucleolytic processing enzyme bound to tRNA. Binding of tRNA to RNase Z causes conformational changes in both partners to promote reorganization of the catalytic site and tRNA cleavage.
About this Structure
2FK6 is a Protein complex structure of sequences from Bacillus subtilis. Full crystallographic information is available from OCA.
Reference
Structure of the ubiquitous 3' processing enzyme RNase Z bound to transfer RNA., Li de la Sierra-Gallay I, Mathy N, Pellegrini O, Condon C, Nat Struct Mol Biol. 2006 Apr;13(4):376-7. Epub 2006 Mar 5. PMID:16518398
Page seeded by OCA on Mon Mar 31 03:03:55 2008
