5nnu | pdb_00005nnu

KSHV uracil-DNA glycosylase, product complex with dsDNA exhibiting duplex nucleotide flipping

spinqualitylabelsall models 5nnu, resolution 2.97Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 5nnu is a 12 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. NonStd Res: AAB Related: 5nnh, 5nn7 Activity: Uracil-DNA glycosylase, with EC number 3.2.2.27 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [Q76RG8_HHV8] Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or deamination of cytosines. Therefore may reduce deleterious uracil incorporation into the viral genome, particularly in terminally differentiated cells which lack DNA repair enzymes.[HAMAP-Rule:MF_04046]

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