2fyo | pdb_00002fyo
From Proteopedia
Crystal structure of rat carnitine palmitoyltransferase 2 in space group P43212
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| 2fyo, resolution 2.00Å | |||||||||||||
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| Ligands: | MSE | ||||||||||||
| Activity: | Carnitine O-palmitoyltransferase, with EC number 2.3.1.21 | ||||||||||||
| Related: | 2fw3, 2DEB
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| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||||||
Overview
Carnitine palmitoyltransferases (CPTs) are part of the enzymatic system that imports fatty acids into mitochondria. The crystal structure of rat CPT-2 by Rufer et al. (2006) (this issue of Structure) reveals a Y-shaped tunnel for binding the CoA and acyl-carnitine substrates and a hydrophobic insert mediating membrane association.
About this Structure
2FYO is a Single protein structure of sequence from Rattus norvegicus. Full crystallographic information is available from OCA.
Reference
A monotopic membrane protein goes solo., Mattevi A, Structure. 2006 Apr;14(4):628-9. PMID:16615901
Page seeded by OCA on Mon Mar 31 03:09:26 2008
