Structural highlights
5vcs is a 2 chain structure with sequence from Human. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
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| Ligands: | BMA, DMS, MAN, NAG, PEG |
| Related: | 5vcm, 5vcr |
| Gene: | MGAT2 (HUMAN) |
| Activity: | Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase, with EC number 2.4.1.143 |
| Resources: | FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT |
Disease
[MGAT2_HUMAN] MGAT2-CDG. The disease is caused by mutations affecting the gene represented in this entry.
Function
[MGAT2_HUMAN] Catalyzes an essential step in the conversion of oligo-mannose to complex N-glycans.
