2huw | pdb_00002huw

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File:2huw.gif


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2huw, resolution 1.900Å
Ligands: PO4, YVN
Gene: GRB2, ASH (Homo sapiens)
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



X-ray crystal structure of the Grb2 SH2 domain complexed to a constrained and cyclopropane-derived ligand


About this Structure

2HUW is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Ligand preorganization may be accompanied by entropic penalties in protein-ligand interactions., Benfield AP, Teresk MG, Plake HR, DeLorbe JE, Millspaugh LE, Martin SF, Angew Chem Int Ed Engl. 2006 Oct 20;45(41):6830-5. PMID:17001728

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