6a4i | pdb_00006a4i

Crystal Structure of human TDO inhibitor complex

spinqualitylabelsall models 6a4i, resolution 2.65Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 6a4i is a 4 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: 9R9, CIT, HEM, TRP Activity: Tryptophan 2,3-dioxygenase, with EC number 1.13.11.11 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [T23O_HUMAN] Incorporates oxygen into the indole moiety of tryptophan. Has a broad specificity towards tryptamine and derivatives including D- and L-tryptophan, 5-hydroxytryptophan and serotonin (By similarity).

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