6dub | pdb_00006dub

Crystal structure of a methyltransferase

spinqualitylabelsall models 6dub, resolution 1.20Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 6dub is a 4 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: GOL, SAH, UNX NonStd Res: 5JP Activity: Protein N-terminal monomethyltransferase, with EC number 2.1.1.299 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [NTM1B_HUMAN] Alpha-N-methyltransferase that methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Pro/Ser]-Pro-Lys when the initiator Met is cleaved. Specifically catalyzes monomethylation of exposed alpha-amino group of Ala or Ser residue in the [Ala/Ser]-Pro-Lys motif and Pro in the Pro-Pro-Lys motif. May activate NTMT1 by priming its substrates for trimethylation.

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