2kvh | pdb_00002kvh

Structure of the three-Cys2His2 domain of mouse testis zinc finger protein

spinqualitylabelsall models 2kvh, 15 NMR models Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 2kvh is a 1 chain structure with sequence from Lk3 transgenic mice. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: ZN Related: 2kvf, 2kvg Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [ZBT32_MOUSE] DNA-binding protein that binds to the to a 5'-TGTACAGTGT-3' core sequence. May function as a transcriptional transactivator and transcriptional repressor (By similarity). Probably exerts its repressor effect by preventing GATA3 from binding to DNA. May play a role in regulating the differentiation and activation of helper T-cells.

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