6ffy | pdb_00006ffy

Structure of the mouse SorCS2-NGF complex

spinqualitylabelsall models 6ffy, resolution 3.90Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 6ffy is a 3 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: BMA, NAG Related: 6fg9 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [NGF_MOUSE] Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival.

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