6ds0 | pdb_00006ds0

Structural Determinants of Activation and Biased Agonism at the 5-HT2B Receptor

spinqualitylabelsall models 6ds0, resolution 3.19Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 6ds0 is a 1 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: CLR, H8M, OLC, PEG Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [5HT2B_HUMAN] This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Plays a role in the regulation of impulsive behavior.

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