6hf3 | pdb_00006hf3

M tuberculosis DprE1 in complex with a covalently bound nitrobenzothiazinone

spinqualitylabelsall models 6hf3, resolution 2.20Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 6hf3 is a 2 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: 26J, FAD Related: 6hez, 6hf0 Activity: Decaprenylphospho-beta-D-ribofuranose 2-oxidase, with EC number 1.1.98.3 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [DPRE1_MYCTU] Involved in the epimerization of decaprenylphosphoryl ribose (DPR) to decaprenylphosphoryl arabinose (DPA) a precursor for arabinan synthesis in mycobacterial cell wall biosynthesis. Probably catalyzes the oxidation at C-2 of decaprenylphosphoryl ribose (DPR) to yield decaprenylphosphoryl 2-keto-ribose (DPX).

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