6a9y | pdb_00006a9y
From Proteopedia
The crystal structure of Mu homology domain of SGIP1
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Structural highlights
Function[SGIP1_HUMAN] May function in clathrin-mediated endocytosis. Has both a membrane binding/tubulating activity and the ability to recruit proteins essential to the formation of functional clathrin-coated pits. Has a preference for membranes enriched in phosphatidylserine and phosphoinositides and is required for the endocytosis of the transferrin receptor. May also bind tubulin. May play a role in the regulation of energy homeostasis (By similarity). Contents | ||||||||||||||||
This page was last modified 07:59, 26 September 2018.