2qux | pdb_00002qux

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File:2qux.jpg


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2qux, resolution 2.44Å
Ligands: A, C, G, GOL, U
Gene: PP7 coat protein (Pseudomonas phage PP7)
Related: 1DWN, 2QUD


Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



PP7 coat protein dimer in complex with RNA hairpin


Overview

The cocrystal structure of the PP7 bacteriophage coat protein in complex with its translational operator identifies a distinct mode of sequence-specific RNA recognition when compared to the well-characterized MS2 coat protein-RNA complex. The structure reveals the molecular basis of the PP7 coat protein's ability to selectively bind its cognate RNA, and it demonstrates that the conserved beta-sheet surface is a flexible architecture that can evolve to recognize diverse RNA hairpins.

About this Structure

2QUX is a Single protein structure of sequence from Pseudomonas phage pp7. Full crystallographic information is available from OCA.

Reference

Structural basis for the coevolution of a viral RNA-protein complex., Chao JA, Patskovsky Y, Almo SC, Singer RH, Nat Struct Mol Biol. 2008 Jan;15(1):103-5. Epub 2007 Dec 9. PMID:18066080

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