5zin | pdb_00005zin

Crystal structure of bacteriorhodopsin at 1.27 A resolution

spinqualitylabelsall models 5zin, resolution 1.27Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 5zin is a 1 chain structure with sequence from Halobacterium salinarum. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: L2P, RET Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [BACR_HALSA] Light-driven proton pump. Publication Abstract from PubMed Bacteriorhodopsin (bR) of Halobacterium salinarum is a membrane protein that acts as a light-driven proton pump. bR and its homologues have recently been utilized in optogenetics and other applications. Although the structures of those have been reported so far, the resolutions are not sufficient for elucidation of the intrinsic structural features critical to the color tuning and ion pumping properties. Here we report the accurate crystallographic analysis of bR in the ground state. The influence of X-rays was suppressed by collecting the data under a low irradiation dose at 15 K. Consequently, individual atoms could be separately observed in the electron density map at better than 1.3 A resolution. Residues from Thr5 to Ala233 were continuously constructed in the model. The twist of the retinal polyene was determined to be different from those in the previous models. Two conformations were observed for the proton release region. We discuss the meaning of these fine structural features. X-ray structure analysis of bacteriorhodopsin at 1.3 A resolution.,Hasegawa N, Jonotsuka H, Miki K, Takeda K Sci Rep. 2018 Sep 3;8(1):13123. doi: 10.1038/s41598-018-31370-0. PMID:30177765 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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