2rf3 | pdb_00002rf3

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Crystal Structure of Tricyclo-DNA: An Unusual Compensatory Change of Two Adjacent Backbone Torsion Angles

File:2rf3.jpg


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2rf3, resolution 1.75Å
Sites: AC1 and AC2
Ligands: DA, DC, DG, DT, SPM, TCY, ZN
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



Overview

The crystal structure of a DNA duplex with tricyclo-DNA (tc-DNA) residues explains the increased RNA affinity of tc-DNA relative to DNA and tc-DNA's superior resistance to nucleases.

About this Structure

2RF3 is a Single protein structure of sequence from [1]. Full crystallographic information is available from OCA.

Reference

Crystal structure of tricyclo-DNA: an unusual compensatory change of two adjacent backbone torsion angles., Pallan PS, Ittig D, Heroux A, Wawrzak Z, Leumann CJ, Egli M, Chem Commun (Camb). 2008 Feb 21;(7):883-5. Epub 2007 Dec 21. PMID:18253536

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