2rf3 | pdb_00002rf3
Crystal Structure of Tricyclo-DNA: An Unusual Compensatory Change of Two Adjacent Backbone Torsion Angles
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| 2rf3, resolution 1.75Å | |||||||||||||
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| Sites: | AC1 and AC2 | ||||||||||||
| Ligands: | DA, DC, DG, DT, SPM, TCY, ZN | ||||||||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||||||
Overview
The crystal structure of a DNA duplex with tricyclo-DNA (tc-DNA) residues explains the increased RNA affinity of tc-DNA relative to DNA and tc-DNA's superior resistance to nucleases.
About this Structure
2RF3 is a Single protein structure of sequence from [1]. Full crystallographic information is available from OCA.
Reference
Crystal structure of tricyclo-DNA: an unusual compensatory change of two adjacent backbone torsion angles., Pallan PS, Ittig D, Heroux A, Wawrzak Z, Leumann CJ, Egli M, Chem Commun (Camb). 2008 Feb 21;(7):883-5. Epub 2007 Dec 21. PMID:18253536
Page seeded by OCA on Mon Mar 31 04:59:39 2008