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ISSN 2310-6301 Because life has more than 2D, Proteopedia helps to understand relationships between structure and function. Proteopedia is a free, collaborative 3D-encyclopedia of proteins & other molecules.
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Coronavirus COVID-19 A novel coronavirus was found to be the cause of a respiratory illness first detected in Wuhan, China in 2019. 3D structural studies are aiding scientists to understand how the coronavirus infects humans and helping to find new ways to treat the viral spread (video by Fusion Animation). >>> Visit this page >>>	Molecular Sculpture by Eric Martz A historical review on sculptures and physical models of macromolecules. >>> Visit this page >>>	Structural flexibility of the periplasmic protein, FlgA, regulates flagellar P-ring assembly in Salmonella enterica. H Matsunami, YH Yoon, VA Meshcheryakov, K Namba, FA Samatey. Scientific Reports 2016 doi: 10.1038/srep27399 A periplasmic flagellar chaperone protein, FlgA, is required for P-ring assembly in bacterial flagella of taxa such as Salmonella enterica or Escherichia coli. Here we present the open and closed crystal structures of FlgA from Salmonella enterica serovar Typhimurium, grown under different crystallization conditions. An intramolecular disulfide cross-linked form of FlgA caused a dominant negative effect on motility of the wild-type strain. >>> Visit this I3DC complement >>>	Tutorial: The Ramachandran principle, phi (φ) and psi (ψ) angles in proteins by Eric Martz The Ramachandran Principle says that alpha helices, beta strands, and turns are the most likely conformations for a polypeptide chain to adopt, because most other conformations are impossible due to steric collisions between atoms. Check Show Clashes to see where non-bonded atoms are overlapping, and thus in physically impossible positions. >>> Visit this tutorial >>>
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Jaime Prilusky, Joel L. Sussman, Angel Herraez