3b2u | pdb_00003b2u
From Proteopedia
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| 3b2u, resolution 2.580Å | |||||||||||||
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| Sites: | AC1, AC2, AC3, AC4, AC5, AC6, AC7, AC8, AC9, BC1, BC2, BC3, BC4, BC5, BC6, BC7, BC8, BC9, CC1, CC2, CC3, CC4, CC5, CC6, CC7, CC8, CC9, DC1, DC2, DC3, DC4, DC5, DC6, DC7, DC8, DC9, EC1, EC2, EC3, EC4, EC5, EC6, EC7, EC8, EC9, FC1, FC2, FC3, FC4, FC5, FC6, FC7, FC8, FC9, GC1 and GC2 | ||||||||||||
| Ligands: | BMA, MAN, NAG, SO4 | ||||||||||||
| Gene: | EGFR (Homo sapiens), EGFR, ERBB1 (Homo sapiens) | ||||||||||||
| Activity: | Receptor protein-tyrosine kinase, with EC number 2.7.10.1 | ||||||||||||
| Related: | 3B2V
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| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||||||
Crystal structure of isolated domain III of the extracellular region of the epidermal growth factor receptor in complex with the Fab fragment of IMC-11F8
Disease
Known disease associated with this structure: Adenocarcinoma of lung, response to tyrosine kinase inhibitor in OMIM:[131550], Nonsmall cell lung cancer, response to tyrosine kinase inhibitor in OMIM:[131550], Nonsmall cell lung cancer, susceptibility to OMIM:[131550]
About this Structure
3B2U is a Protein complex structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Page seeded by OCA on Mon Mar 31 05:22:31 2008
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Homo sapiens
- Protein complex
- Receptor protein-tyrosine kinase
- Ferguson, K M.
- Kussie, P.
- Li, S.
- Alternative splicing
- Anti-oncogene
- Antigen:antibody complex
- Antitumor
- Atp-binding
- Cell cycle
- Cell surface receptor
- Disease mutation
- Drug
- Fab fragment
- Glycoprotein
- Immune system/transferase complex
- Kinase
- Membrane
- Nucleotide-binding
- Phosphoprotein
- Polymorphism
- Secreted
- Transferase
- Transmembrane
- Tyrosine-protein kinase
- Ubl conjugation
